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Cultrex® DIVAA Inhibition Kit

The Directed In Vivo Angiogenesis Assay (DIVAA™) Inhibition Kit was designed for assessing angiogenesis inhibition. The DIVAA was invented to address the short-comings of the plug assay by controlling the site for angiogenesis, increasing reproducibility, conserving test compounds, and supplying more statistical data for quantitative analysis. The kit contains 48 Angioreactors and enough growth factor to induce angiogenesis in all 48 samples. DIVAA has been utilized in demonstrating the inhibition of angiogenesis in matrix metalloprotease (MMP)-2-deficient mice and by TIMP-2.

DIVAA Angiorack Cat# 3450-048-09
Available as a separate product, the autoclavable, reusable Angiorack is precision machined of Teflon® to hold 48 sterile silicone angioreactors in the laminar flow hood while filling and preparing for implantation.


Features: This kit includes pathogen Free BME which has been tested and cleared of a Battery of 31 pathogens and viruses including LDEV. Contact Trevigen for details.
 
Applications: Quantitative in vivo angiogenesis analysis, for the screening of inhibitors.
 
Components: Part # Component Size
  3450-048-01 Angioreactors 48 units
  3450-048-02 Growth Factor Reduced BME PathClear 6 x 200 µl
  3450-048-03 Wash Buffer 25 ml
  3450-048-05 CellSperse™ 15 ml
  3450-048-06 200X FITC-Lectin 250 µg/50 µl
  3450-048-07 25X FITC-Lectin Diluent 400 µl
  3450-048-08 Heparin Solution 10 µl
  3450-048-B10 FGF-2(1800 ng)/VEGF(600 ng) 60 µl
 
  *Basement Membrane Extract (BME)
 
Storage: Components are stored at -20°C and 4°C.
 
References: Guedez L, Rivera AM, Salloum R, Miller ML, Diegmueller JJ, Bungay PM, Stetler-Stevenson WG: Quantitative Assessment of Angiogenic Response by the Directed In Vivo Angiogenesis Assay. AJP 2003, pp 1431-1439.
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Ordering Information
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Catalog #: Price:

3450-048-IK
Directed In Vivo Angiogenesis Assay Inhibition Kit,
48 samples
$575.00
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