Shopping Cart » Cell Assays     » Cell Invasion     » PathClear® BME     » PARP     » CometAssayTM     » HT 8-oxo-dG ELISA  Home » Angiogenesis & Cell Differentiation Angiogenesis & Cell Differentiation Fibroblast Growth Factor-2 (FGF-2, FGF basic) FGF-2 is a potent growth factor that promotes cellular proliferation and differentiation that has been implicated in prenatal development, postnatal growth, and tissue regeneration. FGF-basic is a non-glycosylated heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. Activation of FGF-2 occurs through FGFR 1b, 1c, 2c, 3c and 4. Dramatic amplification of angiogenesis has been observed as a synergistic effect when used in concert with VEGF. FGF-2 is provided in 5 µg aliquots and qualified in the Directed In Vivo Angiogenesis Assay (DIVAA™). Source: DNA sequence corresponding to the mature human FGF-2 (FGF basic) protein was expressed in E. coli.   Activity: The biological activity of recombinant human FGF basic was monitored in a mitogenic assay by measuring the FGF basic dependent 3H-thymidine incorporation in quiescent NR6R-3T3 fibroblasts.   Storage Buffer: 10 mM Tris pH 7.0, 0.3 M glycerin, and 1 mg/mL BSA.   Storage: Store at < -20°C in a manual defrost freezer. Top   Ordering Information Catalog #: Price: 3443-050-02 Cultrex Fibroblast Growth Factor-2, 5 ug $85.00 Trevigen Products are now available for ordering through Download Protocol Related Products Cultrex DIVAA™ Activation Kit Vascular Endothelial Growth Factor (VEGF), Murine TREVIGEN INC. :: 8405 HELGERMAN CT. :: GAITHERSBURG, MD 20877 1.800.TREVIGEN :: 1.800.873.8443 :: (FAX) 1.301.560.4973 :: INFO@TREVIGEN.COM