Shopping Cart » Quantitative PAR ELISA   » 3D Assays   » Stem Cell Assays   » Cell Invasion   » PathClear® BME   » PARP   » CometAssay®  Home » Angiogenesis & Cell Differentiation Angiogenesis & Cell Differentiation Cultrex® 3D Culture Matrix™ BME 3-D Culture is an innovative approach to modeling the morphological effects of early oncogenesis on glandular epithelial cells. When healthy, these cells exhibit a structured, polarized morphology that is critical for cellular formation and function. During carcinoma development, cell cycle controls associated with cellular development, proliferation and death are lost, and as a result, these ascinaric structures are disrupted. In effect, the morphology of these structures can be used as a measure to study factors in early carcinoma development. Trevigen has developed Cultrex 3-D Culture Matrix BME which is the first Basement Membrane Extract produced and qualified specifically for use in 3-D culture studies. Applications: The 3-D Culture Matrix™ provides the foundation for glandular epithelial cells to grow in three dimensions allowing for the formation of ascinar structures in vitro.   Components: Reduced Basement Membrane Extract without phenol red.   Storage: Store at -20° C or -80° C in a manual defrost freezer. Avoid repeated freeze-thaw cycles.   References: Debnath J, Muthuswamy SK, Brugge JS: Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods, 2003 pp. 256-268. Top   Ordering Information Catalog #: Price: 3445-005-01 3D Culture Matrix, 5ml $215.00 3445-001-01 3D Culture Matrix, 1ml $50.00 Trevigen Products are now available for ordering through - AND - Download Protocol 3D Assay Related Products Cultrex Basement Membrane Extract Cultrex 3D Culture Matrix Rat Collagen I Cultrex 3D Culture Matrix Laminin I Cultrex 3D Culture Matrix Cell Harvesting Kit Cultrex 3D Culture 96 Well BME Cell Proliferation Assay Cultrex 3D Culture 96 Well Collagen I Cell Proliferation Assay Cultrex 3D Culture 96 Well Laminin I Cell Proliferation Assay Cultrex 3D Culture Cell Proliferation Assay Core Kit TREVIGEN INC. :: 8405 HELGERMAN CT. :: GAITHERSBURG, MD 20877 1.800.TREVIGEN :: 1.800.873.8443 :: (FAX) 1.301.560.4973 :: INFO@TREVIGEN.COM :: SITE MAP