| Applications: |
Tool for understanding mechanisms involved in bone formation and for identifying potential treatments for osteoporosis, bone repair and genetic disorders such as osteogenesis imperfecta. |
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| Components: |
Part # |
Component1 |
Size |
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5010-024-01 |
Dexamethasone* |
12 µl |
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5011-024-01 |
Ascorbic Acid |
1.2 ml |
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5011-024-02 |
ß-glycerol Phosphate |
1.2 ml |
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3440-001-01 |
Cultrex® Rat Collagen I2 |
500 µl |
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5011-024-03 |
Alizarin Red S3 |
25 ml |
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5011-024-04 |
Stain Solubilization Solution3 |
35 ml |
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1: Reagents are sufficient to differentiate one 24 well plate
2: Sufficient rat tail collagen type I is provided to coat two 24 well plates
3: Enough reagent is provided to test two 24 well plates.
* Separate from shipping box and store at specified temperature
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| Storage: |
Components are stored at -20°C, 4°C, and at room temperature. |
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| References: |
1. Satija NK, Gurudutta GU, Sharma S, Afrin F, Gupta P, Verma K, Singh VK, Tripathi RP. 2007 Mesenchymal Stem Cells: Molecular Targets for Tissue Engineering. Stem Cells and Development 16:7-23.
2. Jones JL, Scotting P, Sottile V. 2007. Adult Mesenchymal stem cell: Differentiation potential and therapeutic applications. J Postgrad Med 53(2): 121-127.
3. Li F, Wang, X, Niyibizi C. 2007. Distribution of Single-Cell Expanded Marrow Derived Progenitors in a Developing Mouse Model of Osteogensis Imperfecta Following Systemic Treatment. Stem Cells. 25:3183-3193.
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