The precursor of cytochrome c, apocytochrome c, is synthesized
in the cytoplasm. Upon translocation into the mitochondria, cytochrome
c refolds and acquires a heme moiety required for functionality
in the mitochondrial respiration chain. The heme-bound form of cytochrome
c is called holocytochrome c.
| Anti-Cytochrome C 4CYTC-21 |
| Catalog #: |
6370-MC-100 |
| |
| Immunogen: |
The antibody was raised against cytochrome c purified from human heart. |
| |
| Source: |
Mouse |
| |
| Specificity: |
The antibody is specific for denatured cytochrome c and apocytochrome c from human, rat, murine, bovine, equine and porcine sources. |
| |
| Subtype: |
IgG1 |
| |
| Anti-Holocytochrome C 2CYTC-199 |
| Catalog #: |
6380-MC-100 |
| |
| Immunogen: |
The antibody was raised against cytochrome c purified from human heart. |
| |
| Source: |
Mouse |
| |
| Specificity: |
The antibody is specific for the heme-bound cytochrome c and will recognize native or denatured human, rat, and murine holocytochrome c. It recognizes only holocytochrome c and no other heme protein (i.e. hemoglobin). This antibody does not cross react with bovine, porcine or equine cytochrome c. |
| |
| Subtype: |
IgG1 |
| |
|
| Preparation: |
Both antibodies are mouse monoclonal antibodies purified on protein G and are provided frozen at 1 mg/ml in PBS. |
| |
| Controls: |
Recombinant apocytochrome c (Cat# 6370-050-01) available separately.
|
| |
| Storage: |
Freeze in working aliquots at -20°C in a manual defrost freezer to avoid repeated freeze-thawing. |
| |
