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Anti-PBR Polyclonal Antibody

The peripheral-type benzodiazepine receptor (PBR) is a ubiquitous protein involved in the regulation of cholesterol transport from the outer to inner mitochondrial membrane. Thought to play a role in the formation of the mitochondrial permeability transition (PT) pore involved in apoptotic mechanisms, PBR is also present in abundance in tumors, in aggressive breast cancer cell lines, and in metastatic human breast tumor biopsy sections.

Immunogen: The anti-PBR antibody was developed in rabbits against an internal sequence of the PBR protein consisting of amino acids 71 to 88 of the human PBR sequence. The specificity of the antibody was assessed in steroidogenic cells and in mitochondrial extracts.
 
Source: Rabbit
 
Specificity:
  • Cat# 6361-PC-100 recognizes mouse, rat, and human PBR protein.
  • Cat# 6362-PC-100 recognizes mouse PBR protein
  •  
    Preparation: PBR antibody is provided as pooled rabbit anti-sera.
     
    Applications:
  • Immunohistochemistry
  • Western blotting
  • Starting recommended dilution for Western blot is 1:1,000; for immunohistochemistry, 1:250.
  •  
    Control: Recombinant PBR protein (Cat# 6360-025-01) available separately.
     
    Storage: Store at -20°C.
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    Ordering Information
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    Catalog #: Price:

    6360-025-01
    PBR Protein (Recombinant),
    25 µl
    $70.00
    Add to Cart

    6361-PC-100
    Anti-Human/Mouse PBR Antibody,
    100µl
    $310.00
    Add to Cart

    6362-PC-100
    Anti-Mouse PBR Antibody,
    100µl
    $310.00
    Add to Cart

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