Trevigen Cell Assays, (TCA) a division of Trevigen, Inc, was established in 2008 to conduct contract research work for the pharmaceutical, biotechnology, government and academic segments of the research market. TCA specializes in designing and conducting assays for lead compound and genotoxic screening based on DNA damage and repair and cancer cell behavior.
Comet Assay Service
Trevigen is the sole provider of a standardized CometAssay® system for the direct detection of DNA Damage. The CometAssay® is a single cell gel electrophoresis assay which can be used to quantitate DNA Damage from in vivo or in vitro samples. The CometAssay® measures double strand breaks (DSBs), single strand breaks (SSBs), alkali labile sites, oxidative DNA base damage, DNA-DNA/DNA-protein/DNA-Drug crosslinking and DNA repair. At your request, the scientists at TCA will collaborate with you to design screening studies employing the CometAssay® tailored for your specific needs.
Comet Assay Service
Advantages
- TCA uses a unique platform of standardized comet assay kits, slides, control cells, CometAssayTM ES electrophoresis system (patent applied for) and state of the art image analysis to assure consistency of results with successive experiments or screening studies.
- The technical team at TCA developed the reagents, slides, control cells and electrophoresis system, and is unmatched in familiarity and skill with the comet assay.
- TCA has already successfully executed multiple comet assay contracts and thus has a proven track record of high performance.
- Confidentiality is assured. TCA is ready to execute Non-Disclosure Agreements as required.
Coming Soon
TCA will soon be expanding its services to offer study design and compound screening services for:
- PARP
- PARG
- Cell invasion
- Cell migration
- Tube formation
- Pharmacodynamic PAR assays will also be offered.
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