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Biotinylated NAD

Trevigen’s biotinylated NAD (6-biotin-17-nicotinamide-adenine-dinucleotide) provides a convenient non-isotopic alternative to radiolabeled NAD for studies requiring this substrate. A number of proteins, including poly (ADP-ribose) polymerase (PARP), use NAD as a substrate for their function. The PARP enzyme catalyzes the polymerization of ADP-ribose onto a number of nuclear proteins. Biotinylated NAD allows an indirect measure of PARP activity when biotin incorporation is detected using a conjugated-streptavidin detection system.

Applications:
  • Activity measurements for NAD requiring enzymes
  • Provided as a buffered solution containing 250 µM 6-biotin-17-nicotinamide-adenine-dinucleotide, sodium salt.
  •  
    Preparation: Provided as a buffered solution containing 250 µM 6-biotin-17-nicotinamide-adenine-dinucleotide, sodium salt.
     
    Molecular Weight: 1179 g/mol
     
    Extinction Coefficient: 22,000 at 265 nm
     
    Purity: >95% by HPLC
     
    Storage: Store at -80°C in working aliquots to avoid repeated freeze-thawing.
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    Ordering Information
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    Catalog #: Price:

    4670-500-01
    Biotinylated NAD,
    500 µl
    $295.00
    Add to Cart

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    TREVIGEN INC. :: 8405 HELGERMAN CT. :: GAITHERSBURG, MD 20877
    1.800.TREVIGEN :: 1.800.873.8443 :: (FAX) 1.301.560.4973 :: INFO@TREVIGEN.COM :: SITE MAP