Trevigen’s unique FLARE™ (Fragment Length Analysis using Repair Enzymes) Assays provide the ability to detect DNA damage in single cells using a variety of DNA repair enzymes in conjunction with Trevigen’s CometAssay™ single cell gel electrophoresis kit. To assess the type of DNA damage induced by a putative mutagen, drug, or treatment regimen, cells are harvested after treatment and immobilized in a layer of low melting point agarose on the FLARE Slide.
| Features: |
FLARE Slides allow direct application of low melting point agarose without base layers or pretreatment for three samples.
Hydrophobic barrier allows easy application of cells directly to slide and treatment with enzyme.
Base specific DNA damage detection.
Convenient format.
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| Applications: |
CometAssayTM
DNA Damage Detection
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| Catalog # |
FLARE Assay |
Damage Recognized |
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4040-100-FK
4040-100-FM |
Fpg |
8-oxoguanine, DNA containing formamidopyrimidine moieties |
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4045-01K-FK
4045-01K-FM |
Endonuclease III |
Thymine Glycol, 5,6-dihydrothymine, urea, 5-hydroxy-6-hydrothymine, 5,6-dihydrouracil, alloxan, 5-hydroxy-6-hydrouracil, uracil glycol, 5-hydroxy-5-methylhydantoin, 5-hydroxycytosine,5-hydroxyuracil,methyltartonylurea, thymine ring saturated or fragmentation product |
4130-100-FK
4130-100-FM |
hOGG1 |
8-oxoguanine, DNA containing formamidopyrimidine moieties |
4055-100-FK
4055-100-FM |
T4-PDG |
Cis-syn isomers of cyclobutane pyrimidine dimers |
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4065-100-FK
4065-100-FM |
cv-PDG |
Cis-syn and trans-syn isomers of cyclobutane pyrimidine dimers |
4100-100-FK
4100-100-FM |
UVDE |
Cyclobutane pyrimidine dimers, (6-4) photoproducts |
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| Storage: |
Store components at -80ºC, -20ºC, 4ºC, and room temperature |
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Ordering Information
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Catalog #:
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Price:
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3950-075-SP
FLARE Sample Prep,
75 tests |
$130.00
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4040-100-FM
E. coli Fpg FLARE Module,
>100 Samples |
$315.00
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4040-100-FK
E. coli Fpg. FLARE Kit,
75 samples |
$340.00
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4045-01K-FM
E. coli Endonuclease III FLARE Module,
>100 Samples |
$315.00
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4045-01K-FK
E. coli Endonuclease III FLARE Kit,
>75 Samples |
$340.00
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4130-100-FM
hoGG1 FLARE Module,
100 Samples |
$315.00
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4130-100-FK
hoGG1 FLARE Kit,
75 samples |
$340.00
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4055-100-FK
T4-PDG FLARE Kit,
75 samples |
$340.00
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4055-100-FM
T4-PDG FLARE Module,
>100 Samples |
$315.00
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4065-100-FM
cv-PDG FLARE Module,
>100 Samples |
$315.00
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4065-100-FK
cv-PDG FLARE Kit,
75 samples |
$340.00
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4100-100-FM
S. pombe UVDE FLARE Module,
>100 Samples |
$315.00
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4100-100-FK
S. pombe UVDE FLARE Kit,
75 samples |
$340.00
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4045-01K-EB
E. coli Endonuclease III Enzyme & Buffer,
1000 Units |
$260.00
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Trevigen Products are now available for ordering through
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